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Berkalp Doganer

Bachelors Student in Nanobiology
(Feb. 2015 - Jan. 2016)
with M.Sc. in Nanobiology (2017)
Delft University of Technology


From February to June of 2015, Berkalp performed his bachelors thesis project in our lab. After completing his thesis, he returned to our lab to teach bachelors students who joined our lab after him and to write a review on bridging the gap between autocrine signaling and quorum sensing. Quorum sensing and autocrine signaling have traditionally been thought to be two disparate forms of cellular communication. Up until recently, quorum sensing has primarily been studied in microbial cells. Autocrine signaling has primarily been studied in animals and plants. Quorum sensing focuses on one cell communicating with its neighboring cell. Autocrine siganling focuses on one cell communicating with itself. Berkalp's review succintly outlines recent studies that have revealed connections between the two that are being appreciated and recognized only in recent years. Namely, a so-called "autocrine cell" can also communicate with its neighboring cells and a quorum sensing cell can also communicate with itself. In short, a cell that "secretes and senses" can talk to itself and talk to others, all with just one extracellular signalling molecule and one receptor. Berkalp was our lab's first bachelors student. In fact, he and Théo Maire were our lab's first students. Aside from the review article that he has authored and starting up a new project on using budding yeasts to reveal design principles of multicellular systems, Berkalp played a crucial role in setting up our lab. He has engineered a number of genetic circuits in yeasts that are now invaluable for several projects in our lab. We're all very thankful to Berkalp for his contributions to our lab. He was a model citizen in our lab. We wish him all the best in the future.

Publication of Berkalp Doganer from our lab:

B. Doganer, L. K. Q. Yan & H. Youk
Autocrine signaling and quorum sensing: Extreme ends of a common spectrum
Trends in Cell Biology (E-Pub ahead of print: Dec. 2015)
   review (.pdf)       pubmed   

In his own words:

(Written during his time in our lab)
As Albert Einstein once said "The important thing is not to stop questioning. Curiosity has its own reason for existing”. I have always been very curious and eager to learn new things, whether it is about science, history or other cultures. This interest in learning new things eventually led me to study Nanobiology at the TU Delft & Erasmus MC, because I believed that life itself was one of the greatest mysteries that still needed to be ‘solved’. And after 2.5 years I can say that it has been a great decision since life itself has started to fascinate me even more. Therefore I am really thrilled to do my Bachelor End Project (BEP) in the Youk Lab at the Bionanoscience department in Delft. When I am not in the lab, I enjoy reading, watching movies, and spending quality time with friends and family. I also like to travel in order to see more of the world that we live in. Furthermore I also like to play football, which is necessary to keep myself in shape as I also like to treat myself with nice meals from different cuisines.