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About the cover image: The image shows a montage of yeast spores showing RNAP II (red) level on different days of ageing (rows). Spore age increases by days from left to right and RNA polymerase II level increases from top to bottom. Cover concept and image by Théo Maire. T. Maire, T. Allertz, M.A. Betjes, H. Youk. Dormancy-to-death transition in yeast spores occurs due to gradual loss of gene-expressing ability Molecular Systems Biology 16:e9245 (2020)